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14: 00 - 17: 30 Poster Session 2 Poster Area Posters must be set up between 13: 00 and 13: 30, removed between 17: 30 and 18: 00 and be on display between 13: 30 and 17: 30. The author should be present during the coffee break 15: 30 to 16: 00 ; in order to discuss the poster. The first five abstracts below will be discussed in a dedicated area in the Exhibition Hall and chaired by two chairpersons from 15: 30 to 16: 00. Moderated Posters: Precipitating factors for heart failure Chairpersons: R. Ferrari Ferrara, IT J.-J. Mercadier Paris, FR ; Suppressors of hypertrophy in concentric and eccentric hypertrophy and upon the transition to failure. K. Lemmens, V.F.M. Segers, M. Demolder, V. Michiels, P Muylaert, E. De Worm, . P Van Cauwelaert, G.W.A. De Keulenaer Antwerp, BE ; .H. Cardiac function and efficiency are dependent on FFA availability in patients with idiopathic dilated cardiomyopathy. H. Tuunanen, E. Engblom, L.H. Opie, B. Hesse, J. Airaksinen, P Nuutila, . H.J. Ukkonen, J.M. Knuuti Copenhagen, DK; Observatory, ZA; Turku, FI ; Changing proportion of patients with dilated cardiomyopathy with SCDHeFT and CARE-HF Companion characteristics during follow-up on optimal medical treatment. M. Zecchin, A. Di Lenarda, M. Merlo, A. Pivetta, D. Gregori, D. Chicco, F. Brun, G.F. Sinagra Turin, Trieste, IT ; Direct arrhythmogenic effects of angiotensin II and endothelin-1 in human atrial myocardium from patients with sinus rhythm. J. Kockskaemper, S.-U. Ruebertus, E. Sigirci, B.M. Pieske Gottingen, DE ; Adiponectin attenuates angiotensin II-induced hypertrophy by inhibiting the c-Raf-ERK1 2 pathway via Akt activation. D.-J. Choi, M.C. Choi, E.-S. Jeon, J.J. Kim, K.H. Ryu Chungju, Seongnam, Seoul, KR ; Heart lung ; transplantation NT-pro BNP evaluation as a non-invasive marker of rejection after heart transplantation. M. Knazeje, I. Malek, M. Kment, B. Raska, J. Pirk Martin, SK; Prague, CZ ; Thymoglobuline administered early after heart transplantation oht ; protects myocardial hypertrophy assessed by karyometric studies. M.W. Zakliczynski, J. Nozynski, E. Zembala-Nozynska, M. Zembala, Konecka-Mrowka D. Zabrze, PL ; Marginal heart donors for marginal recipients of combined heart and lung transplantation: Case reports. T. Ben Gal, M.R. Kramer, A. Kogan, R. Michovitch, I. Backal, V. Yaari, A. Battler, G. Sahar Petah Tikva, Ramat Hasharon, IL ; Predictors of mortality for Chagas' disease patients on the waiting list for heart transplantation. R. Bestetti, T. Theodoropoulos, J.A. Cordeiro, D. Villafanha Ribeirao Preto, Sao Jose do Rio Preto, BR ; w ; : Withdrawn P204 P199, for example, imodium as.
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162. Gordon NF, Gulanick M, Costa F, Fletcher G, Franklin BA, Roth EJ, Shephard T, for the American Heart Association Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention; the Council on Cardiovascular Nursing; the Council on Nutrition, Physical Activity, and Metabolism; and the Stroke Council. Physical activity and exercise recommendations for stroke survivors: an American Heart Association scientific statement from the Council on Clinical Cardiology, Subcommittee on Exercise, Cardiac Rehabilitation, and Prevention; the Council on Cardiovascular Nursing; the Council on Nutrition, Physical Activity, and Metabolism; and the Stroke Council. Stroke. 2004; 35: 1230 Duncan P, Studenski S, Richards L, Gollub S, Lai SM, Reker D, Perera S, Yates J, Koch V, Rigler S, Johnson D. Randomized clinical trial of therapeutic exercise in subacute stroke. Stroke. 2003; 34: 21732180. MacKay-Lyons MJ, Makrides L. Cardiovascular stress during a contemporary stroke rehabilitation program: is the intensity adequate to induce a training effect? Arch Phys Med Rehabil. 2002; 83: 1378 Fletcher GF, Balady GJ, Amsterdam EA, Chaitman B, Eckel R, Fleg J, Froelicher VF, Leon AS, Pina IL, Rodney R, Simons-Morton DA, Williams MA, Bazzarre T. Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. Circulation. 2001; 104: 1694 Sacco RL, Gan R, Boden-Albala B, Lin IF, Kargman DE, Hauser WA, Shea S, Paik MC. Leisure-time physical activity and ischemic stroke risk: the Northern Manhattan Stroke Study. Stroke. 1998; 29: 380 Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis: North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med. 1991; 325: 445 MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe 70 99% ; or with mild 0 29% ; carotid stenosis: European Carotid Surgery Trialists' Collaborative Group. Lancet. 1991; 337: 12351243. Mayberg MR, Wilson SE, Yatsu F, Weiss DG, Messina L, Hershey LA, Colling C, Eskridge J, Deykin D, Winn HR. Carotid endarterectomy and prevention of cerebral ischemia in symptomatic carotid stenosis: Veterans Affairs Cooperative Studies Program 309 Trialist Group. JAMA. 1991; 266: 3289 Barnett HJ, Taylor DW, Eliasziw M, Fox AJ, Ferguson GG, Haynes RB, Rankin RN, Clagett GP, Hachinski VC, Sackett DL, Thorpe KE, Meldrum HE, Spence JD. Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis: North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med. 1998; 339: 14151425. Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European Carotid Surgery Trial ECST ; . Lancet. 1998; 351: 1379 Streifler JY, Eliasziw M, Benavente OR, Harbison JW, Hachinski VC, Barnett HJ, Simard D. The risk of stroke in patients with first-ever retinal vs hemispheric transient ischemic attacks and high-grade carotid stenosis: North American Symptomatic Carotid Endarterectomy Trial. Arch Neurol. 1995; 52: 246 Kappelle LJ, Eliasziw M, Fox AJ, Sharpe BL, Barnett HJ. Importance of intracranial atherosclerotic disease in patients with symptomatic stenosis of the internal carotid artery: the North American Symptomatic Carotid Endarterectomy Trial. Stroke. 1999; 30: 282286. Henderson RD, Eliasziw M, Fox AJ, Rothwell PM, Barnett HJ. Angiographically defined collateral circulation and risk of stroke in patients with severe carotid artery stenosis: North American Symptomatic Carotid Endarterectomy Trial NASCET ; Group. Stroke. 2000; 31: 128 Rothwell PM, Eliasziw M, Gutnikov SA, Warlow CP, Barnett HJ; Carotid Endarterectomy Trialists Collaboration. Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery. Lancet. 2004; 363: 915924. Failure of extracranial-intracranial arterial bypass to reduce the risk of ischemic stroke: results of an international randomized trial: the EC IC Bypass Study Group. N Engl J Med. 1985; 313: 11911200. Grubb RL Jr, Derdeyn CP, Fritsch SM, Carpenter DA, Yundt KD, Videen TO, Spitznagel EL, Powers WJ. Importance of hemodynamic factors in the prognosis of symptomatic carotid occlusion. JAMA. 1998; 280: 10551060. Schmiedek P, Piepgras A, Leinsinger G, Kirsch CM, Einhupl K. Improvement of cerebrovascular reserve capacity by EC-IC arterial bypass surgery in patients with ICA occlusion and hemodynamic cerebral ischemia. J Neurosurg. 1994; 81: 236, because imodium akut.
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Masubuchi Y, Yamada S, and Horie T. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal antiinflammatory drugs. J Pharmacol Exp Ther 292: 982-987, 2000.
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Medicinal plants--Therapeutic use 1 ; Yaowarate Intiyot. Effects of Murdannia loriformis extract on azoxymethane-induced DNA-adducts and aberrant crypt foci in rat colons. Chiang Mai : Chiang Mai University, 1999. 79 p. T E13431 ; Medicine Paweena Phanthama. The organization and the linguistic features of the abstracts of medical journals. Bangkok : Mahidol University, 2000. 138 p. T E15214 ; Yan, Jin. Selected factors associated with medical fear among hospitalized Chinese school-age children. Chiang Mai : Chiang Mai University, 1997. 89 p. T E11776 ; Medicine, Botanic Kannikar Kumput. Description and key of some medicinal fruits. Chiang Mai : Chiang Mai University, 1983. x, 128 p. R E1502 ; Noppamas Soonthronchareonnon. A study on the chemistry and in-vitro antimalarial activity of Eurycoma longifolia Jack and other Thai medicinal plants. Bangkok : Mahidol University, 1982. xvii, 86 p. T E6274 ; Medicine, Chinese Wang, Zenghong. Patients' satisfaction towards current traditional Chinese medicine services at Huw Chiew General hospital in Bangkok, Thailand. Bangkok : Mahidol University, 2001. 72 p. T E16965 ; Medicine, Preventive Patthana Tanasestt. The compliance of implementation for the control of iodine deficiency disorders. Bangkok : Mahidol University, 1996. 267 p. T E10476 ; Medicine, Preventive--China Jiang, Yuan. Allocative efficiency and equity of public health budget in three provinces of China. Bangkok : Chulalongkorn University, 1996. 88 p. T E11843 ; Medicine, Traditional Phuong, Do Thi. Factors effecting the use of traditional medicine and western medicine in Prachinburi 1994. Bangkok : Mahidol University, 1994. iv, 80 p. T E7145 ; . Traditional treatments experienced by schizophrenic patients and relatives prior to medical treatment in Khon Kaen Neuropsychiatric hospital. : , 2539. 67 . 98879 .1; 104680 ; Medicine--Equipment and supplies . Design and construction of a neonatal respiration monitor. : , 2542. 22 . 99777 .1; 99902.
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Syphilis can cause a range of symptoms or none at all, but if left untreated can have very serious effects on the brain and the rest of the nervous system known as neurosyphilis ; . In HIV-positive people, the small sore or ulcer chancre ; associated with initial infection primary syphilis ; can appear as unusual or multiple ulcers, and may be mistaken for an attack of genital herpes, which can happen at the same time. It can also be totally missed by both patient and doctor. Consequently, syphilis is more often diagnosed in HIV-positive people when it has progressed to the often symptomatic secondary stage, when it shows up in blood tests. "The experience in Manchester is that more patients with HIV are likely to be symptom-free with their primary disease and yet present with more florid secondary disease, " says Dr Ed Wilkins of North Manchester General Hospital. "In our clinic we have certainly picked up more cases of secondary syphilis due to the characteristic rash affecting the palms and soles, " confirms Birmingham's Stephen Taylor. It can take up to 90 days for the body to develop antibodies to the bacteria that cause syphilis, so a blood test immediately after exposure to syphilis may not detect infection. Some studies have suggested that these tests are not as effective in people with HIV; in fact, some HIV-infected people who do have syphilis may test negative. Since 2002, the HIV Special Interest Group of the British Association of Sexual Health and HIV BASHH ; , chaired by Martin Fisher, has recommended that in an outbreak situation, a blood test for syphilis should take place every three months, at the same time as routine CD4 counts and viral.
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Table 3 Increase in Nelfinavir AUC, Cmax and Tmax in Fed Low Fat 20% ; versus High Fat 50% ; State Relative to Fasted State Following 1250 mg VIRACEPT 5 x 250 mg tablets ; Number of Kcal % Fat Number of subjects AUC fold increase Cmax fold increase Increase in Tmax hr ; 20 n 3.1 2.5 n 22 5.1 3.8 Nelfinavir exposure can be increased by increasing the calorie or fat content in meals taken with VIRACEPT. A food effect study has not been conducted with the 625 mg tablet. However, based on a cross-study comparison n 26 fed vs. n 26 fasted ; following single dose administration of nelfinavir 1250 mg, the magnitude of the food effect for the 625 mg nelfinavir tablet appears comparable to that of the 250 mg tablets. VIRACEPT should be taken with a meal. Distribution: The apparent volume of distribution following oral administration of nelfinavir was 2-7 L kg. Nelfinavir in serum is extensively protein-bound 98% ; . Metabolism: Unchanged nelfinavir comprised 82-86% of the total plasma radioactivity after a single oral 750 mg dose of 14C-nelfinavir. In vitro, multiple cytochrome P-450 enzymes including CYP3A and CYP2C19 are responsible for metabolism of nelfinavir. One major and several minor oxidative metabolites were found in plasma. The major oxidative metabolite has in vitro antiviral activity comparable to the parent drug. Elimination: The terminal half-life in plasma was typically 3.5 to 5 hours. The majority 87% ; of an oral 750 mg dose containing 14C-nelfinavir was recovered in the feces; fecal radioactivity consisted of numerous oxidative metabolites 78% ; and unchanged nelfinavir 22% ; . Only 1-2% of the dose was recovered in urine, of which unchanged nelfinavir was the major component. Special Populations Hepatic Insufficiency: The multi-dose pharmacokinetics of nelfinavir have not been studied in HIV-positive patients with hepatic insufficiency. Renal Insufficiency: The pharmacokinetics of nelfinavir have not been studied in patients with renal insufficiency; however, less than 2% of nelfinavir is excreted in the urine, so the impact of renal impairment on nelfinavir elimination should be minimal. Gender and Race: No significant pharmacokinetic differences have been detected between males and females. Pharmacokinetic differences due to race have not been evaluated. Pediatrics: The pharmacokinetics of nelfinavir have been investigated in 5 studies in pediatric patients from birth to 13 years of age either receiving VIRACEPT three times or twice daily. The dosing regimens and associated AUC24 values are summarized in Table 4. Table 4 Summary of Steady-state AUC24 of Nelfinavir in Pediatric Studies N2 Dosing regimen1 Protocol no. AG1343-524 PACTG-725 PENTA 7 PENTA 7 PACTG-353 20 19-28 ; mg kg TID 55 48-60 ; mg kg BID 40 34-43 ; mg kg TID 75 55-83 ; mg kg BID 40 14-56 ; mg kg BID 14 6 4 and sorbitrate!
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Metronidazole is the only antibiotic with an accepted role in the treatment of IBD. Its use is confined to Crohn's disease - most commonly to control anal complications such as abscesses or fistulas. It has also been shown to have some beneficial effect in Crohn's disease at other sites, particularly the large bowel. It is not known whether the effect of metronidazole is due to its antibiotic activity ie. its ability to kill bacteria ; . The most common side-effects are nausea and loss of appetite, indigestion, a metallic taste in the mouth, diarrhoea and headache occur less frequently. Prolonged treatment with metronidazole can damage the nerves in the feet and arms, leading to tingling and numbness. This is reversible on stopping the drug but may take some months to return to normal. Some people have an unpleasant reaction to alcohol flushing of the face, headache, palpitations, nausea, shortness of breath and drowsiness ; while they are taking metronidazole. It is probably best to abstain from alcohol. B. NON-SPECIFIC DRUGS 5. Anti-diarrhoeal Drugs Loperamide Imodium, Dicap ; , diphenoxylate + atropine Lomotil ; and codeine phosphate reduce diarrhoea but have no effect on the inflammation which is causing diarrhoea. They are related to narcotic drugs such as morphine but have a much lower risk of addiction, especially loperamide and Lomotil. They work mainly by reducing the contraction of the muscle in the bowel wall, slowing the movement of bowel contents through the gut. They also cause some reduction of the amount of fluid produced by the lining of the gut. These drugs should not be used in children or in a severe attack of colitis, when they may cause the bowel to enlarge and burst. They can be useful to control diarrhoea during milder attacks of IBD, or in patients who have diarrhoea even though their disease is inactive. The main side-effect is constipation. Other side-effects are unusual, although probably more common with codeine phosphate than with loperamide and Lomotil. Drowsiness, headache, mood changes and skin rashes can occur. Lomotil contains atropine, which can cause a dry and tofranil.
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Let me preempt this section by emphasizing that every man is different. You'll need to find out what works best for you. Loading up on your supplement of choice for several days with NO sex or masturbation ; is suggested before you will notice any change in your ejaculate volume. So don't expect immediate results the first day you start in on a supplement. As you'll read later in the General Health section, if you try a supplement but continue to smoke & drink heavily, consume a diet rich in ALL the wrong foods, you're too tired, you cum 30 seconds after you start, then you may not notice a difference in your ejaculate volume as quickly as those who practice better health and drink enough water every day.
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This program has done little to reduce the nation's marijuana supply, however, as 9 42 percent of eradicated marijuana in 2001 the most recent year data is available ; was ditchweed, or feral hemp, which contains miniscule quantities of thc and therefore has no value as a street drug.
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Even if those drugs are approved, though, they will be competing with a brand so famous it recalls bayer's blockbuster drug from nearly a century ago - aspirin.
The second EuroLAM meeting in September 2004 was attended by 13 doctors from France, Germany, Italy, Ireland, Switzerland, Spain, the UK and the US. Five patient representatives also attended, including Lucy Falconer and Gill Hollis from the UK, and the event was hosted brilliantly! ; by the Nottingham team. Two main topics were on the agenda first, EuroLAM itself; what its aims and objectives should be and how it should be organised and funded, and second, the rapamycin trials; updates on the first trial currently taking place in the US and the plans for a second trial which may be extended to include European centres. The two topics are related the inclusion of European patients in clinical trials would be made far easier if there is cooperation between European doctors specializing in LAM. Michelle Gonsalves, the French LAM patient who has been the main driving force behind EuroLAM, introduced the meeting. She illustrated the benefits of European cooperation by reporting that the questionnaire on flying had generated 140 responses across Europe. The results are still being collated, but this is a very large number of responses relative to our small LAM population. With a disease as rare as LAM it is important to get as many responses as possible in order that the data becomes meaningful. Aims and Organisation of EuroLAM Anne Tattersfield chaired sessions on what the aims, objectives and organisation of EuroLAM should be. Broadly, it was agreed that the aims should be i ; to facilitate research in Europe by sharing expertise, being able to access patients rapidly for clinical trials and accessing European funding, ii ; to provide support for people with LAM by providing information on LAM, supporting national societies and helping new ones to develop, and accessing European funding, and possibly iii ; to establish clinical guidelines of best practice for physicians. However, whilst there was considerable discussion, there was no definitive conclusion on how EuroLAM should be organised and funded. There appeared to be agreement that EuroLAM should involve both patients and physicians perhaps being a loose affiliation of national LAM patient associations and while there was recognition that EuroLAM would need some sort of permanent support in the form of someone working parttime, with an office ; , there was no conclusion on who this person would be, where they would be based or how they would be funded. One possibility would be for the person who was helping co-ordinate the rapamycin trials in Europe see below ; to spend two days a week on EuroLAM, if funding could be found. Anne had arranged for David Crowley, a member of staff at Nottingham University, to talk about how EuroLAM might get European funding. The good news is that from time to time, there is EC funding available to aid research and support people with rare diseases, but!
Fda advises patients to stop taking these medicines, and call a doctor or healthcare provider right away if they experience sudden or decreased vision loss in one or both eyes, for example, imodium and pregnancy.
From the divisions of pulmonary and critical care medicine drs krishnan and diette ; and general medicine dr wu ; , department of medicine, the johns hopkins school of medicine, and departments of epidemiology dr diette ; and health policy and management mss skinner and clark and drs steinwachs and wu ; , the johns hopkins school of hygiene and public health, baltimore, md and loperamide.
A2 8: 45 ACTIVITY-DEPENDENT INHIBITORY SYNAPTIC PLASTICITY IN THE ZEBRAFISH DANIO RERIO ; . Cheung Una * , Ryan Geraldine * , Kermanshahi Sanaz * , Woodin Melanie. Department of Zoology, 25 Harbord Street, University of Toronto, Toronto, Canada, M5S 3G5. Modifications of synaptic strength are believed to underlie the development of neuronal connectivity, learning and memory functions of the nervous system and the ability of organisms to adapt to their ever-changing environment. While the synaptic plasticity of excitatory synapses is well understood, the ability of inhibitory synapses to undergo modification has received much less attention, despite recent evidence on their critical roles in neuronal network activity. In order to determine the role of inhibitory synaptic plasticity in the intact animal we have developed an in vivo zebrafish preparation where sensory-induced modifications in inhibitory synaptic transmission in the tectum can be recorded electrophysiology and imaged using fluorescent markers. We are specifically examining the retinotectal system of the zebrafish due to its simple well-characterized neuroanatomy; retinal ganglion cells make direct contralateral GABAergic synapses with neurons of the optic tectum. Anesthetized zebrafish MS-222 final concentration 0.01% ; are embedded in low-melting agarose dorsal side up; after the agar has hardened the tectum is exposed and covered with zebrafish extracellular solution. A fine needle is then used to remove the skin overlaying the dorsal surface of the CNS exposing the tectal cells. Activity-induced inhibitory synaptic plasticity can be assessed by stimulating the retina with light and making electrophysiological recordings from the tectal neurons. The tectum serves as the first processing centre for complex behavioural tasks including orientation toward prey and away from predators. Inhibitory synaptic plasticity will be correlated with two well described visual-motor responses: the optokinetic response OKR ; which allows the tracking of moving patterns and the reflexive swimming optomotor response OMR ; which helps maintain stable position in response to movement of visual cues. Thus, the ability to perform combined electrophysiological and fluorescence imaging experiments and correlate these data with the results from behavioural analysis make the zebrafish an ideal model system for the study of activity-dependent inhibitory synaptic plasticity. Supported by the NSERC.
Had to come off that drug and never go back on it.
By brand 2000 Remicade arthritis Rx .29, 005 Band-Aid bandages 25, 669 Procrit anemia Rx .25, 458 Imodkum AD remedies 23, 243 Monistat yeast cream 20, 793 Clean & Clear skincare 19, 154 Lactaid milk 17, 991 Nizoral dandruff Rx .16, 134 Mylanta antacids 15, 179 Reach toothbrushes 15, 000 Aveeno toiletries 14, 892 Stayfree maxi pads 12, 341 OB tampons 11, 949 Sales & earnings $ in millions ; Worldwide 2000 Sales $29, 139 Earnings 4, 800 U.S. 2000 Sales 17, 000 Division sales 2000 Pharmaceutical 11, 954 Professional 10, 281 Consumer 6, 904 1999 0 27, 297 15, % chg NA -6.0 67.7 29.9 -23.7 -24.3 554.8 -38.0 11.7 -30.3 462.5 -42.6 0.4 Orthopedics: Arrco Medical Advertising, Norwood, Mass. Jerome Reicher, pres & creative dir. Devine & Pearson, Quincy, Mass. John Pearson, partner & creative dir. Johnson & Johnson Worldwide Advertising Group: 410 George St., New Brunswick, N.J. 08901 Phone: 732 ; 524-0400. Andrea Alstrup, corp VP-adv. Media buying-Hispanic: Casanova Pendrill Publicidad, Irvine, Calif. Laura Marella, VP & media dir. Media buying-print: Advanswers, St. Louis. Joe Rousseau, sr VP & exec dir; Lee Zobrist, VP & project dir. Media buying-TV: Universal McCann, New York. Donna Wolfe, exec VP & dir-natl bdcast; Sande Bovis, sr VP & assoc dir. McNeil Consumer Healthcare Nutritionals Worldwide: 7050 Camp Hill Rd., Fort Washington, Pa. 19034 Phone: 215 ; 273-7000. W. Anthony Vernon, pres; William L. McComb, VP-mktg & prof sls; Peter Valenti, franchise director. Hispanic adv: Bienestar, Princeton, N.J. Craig Scott, pres. Interactive: MarketSource, Cranbury, N.J. Michael Konowicz, dir-strategy & media. Prescription nonprescription pharmaceuticals: Lowe Lintas & Partners, New York. Kieran Walsh, grp dir; Tish Bischoff, grp media dir. Prescription nonprescription pharmaceuticals: Saatchi & Saatchi, New York. Barbara Borg, grp comms dir. Prof: Nelson Communications, New York. Barbara Renta, pres & chief operating officer. Neutrogena Corp.: 5760 W. 96th St., Los Angeles, Calif. 90045 Phone: 310 ; 642-1150. Michael McNamara, pres; Cindy Zielinski, VP-mktg, skin, hair & suncare; M. Bolyard, VP-mktg, cosmetics; James Colleran, sr VP-mktg & sls. Carlson & Partners, New York. Liz Laarouchi, sr VP-grp acct dir; Colleen Rizzo, sr principal media dir. Ortho Biotech: P.O. Box 670, U.S. Route 202, Raritan, N.J. 08869-0602 Phone: 908 ; 704-5000. Gary Reedy, pres. Kevin Porter Group, New York. Kevin Porter, media dir. OgilvyOne, New York. Allison Womack, sr partner & client svcs dir-healthcare. Ortho-Dermatological: P.O. Box 300, Skillman, N.J. 08869 Phone: 908 ; 904-3300. William D. Cordivari, pres. Adient, Wayne, N.J. Jim Clifford, pres; Ed Keegan, exec VP & mg ptnr; Rich Norman, exec VP, chief creative officer & mg ptnr. Carlson & Partners, New York. Liz Laarouchi, sr VP-grp acct dir. Ortho-McNeil Pharmaceutical: 1000 U.S. Route 202 South, Raritan, N.J. 08869 Phone: 908 ; 218-6000. Seth Fischer, pres; Robin Sears, VP-mktg, women's health. Adient, Wayne, N.J. Ed Keegan, exec VP & mg ptnr; Richard Norman, exec VP, chief creative officer & mg ptnr. CommonHealth, Parsippany, N.J. Phil Brady, CEO. Thomas Ferguson Associates, Parsippany, N.J. David Chapman, pres. Healthworld Corp., New York. Linda Gill, exec VP. Lowe Lintas & Partners, New York. Kieran Walsh, grp dir; Tish Bischoff, grp media dir. Personal Products Co.: Grandview Rd., Skillman, N.J. 08558 Phone: 908 ; 874-1000. Patrick Mutchler, pres. Lowe Lintas & Partners, New York. Kieran Walsh, grp dir; Tish Bischoff, grp media dir. McCann-Erickson Worldwide, New York. Claire Roundal, grp mg dir-Stayfree, Monistat, oral care. Vistakon: P.O. Box 10157, Jacksonville, Fla. 32247 Phone: 904 ; 443-1000. Phil Keefer, pres; Bob Muiolo, VP-mktg. Vision care: McCann-Erickson Worldwide, New York. Kimberly Pennington, sr VP & grp mg dir.
Certain conditions do not inevitably lead to specific mental disorders, except in the few cases noted. Prevention is often a "shot in the dark" in this sense. Health promotion, on the other hand, has a more tangible and identifiable target, namely the improvement or development of observable skills and behaviors identified as mentally healthy. General strategies applied in preventing mental illness: case-finding through surveys, routine medical or developmental assessments, or other agency referral early psychosocial intervention prompt diagnosis and referral for treatment examination of the social and environmental correlates of mental illnesses and the psychosocial stressors provision of services and promotion of social and environmental change. Both the prevention and health-promotion strategies of healthcare call for a change in caregiver attitudes concerning causation, away from an individualistic and individual pathology model and toward a more socially and community-oriented approach to causation and intervention. Prevention and mental health promotion are best achieved by a coordinated network of services and agencies. Responsibility for mental health is ultimately diffused throughout the community, and the tasks of mental health workers are to convey this message to the community and to activate its members. A caution should be observed in initiating any community program. No matter how apparently benign, any intervention that is powerful or comprehensive enough to produce beneficial outcomes may also produce undesirable side effects. Smaller, less ambitious interventions are perhaps safer if for no other reason than that their potential for harm is less. PREVENTABLE PSYCHIATRIC DISORDERS Genuine disease-specific prevention of mental disorders is recognized as possible in about five categories of disease, and this is true in part only because the causes are known in these instances.
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